Table 2 Summary of neuronal ion channel gene expression in TAF1-depleted cells by qRT-PCR array analysis
Gene symbolGene descriptionLog 2 fold change
ASIC2ASIC2 plays a role in neurotransmission6.03
ASIC3ASIC3 may play an important role in the detection of lasting pH changes3.88
KCNJ14KCNJ14 probably has a role in controlling the excitability of motor neurones2.74
CACNG4CACNG4 regulates both trafficking and channel gating of the AMPA receptors2.00
KCNAB3KCNAB3 regulates the activity of the α subunit2.00
CACNA1GCACNA1G subunit mediates the entry of calcium ions into excitable cells; also involved in a variety of calcium-dependent processes−2.00
HCN2HCN2 involved in the generation of native pacemaker activity in the heart and in the brain−2.00
KCNH2KCNH2 is a voltage-activated potassium channel belonging to the eag family−2.21
  • Abbreviation: AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor.